I have a 50 cal Encore in which I shoot 100 grains of Pyrodex. I have shot 130, and 150 grains out of it with good results. That said I went back to 100 grains for the simple reason it was cheaper to shoot, and I felt I wasn't "leaving anything on the table" by backing down. If your trying to stretch your capabilities to the max with heavy bullets/long distance then go big. If your trying to make reasonable shots then 100 grains is good.
In reply to your other post, I shoot the Hornady SST bullets and have had great results. I shot powerbelts and wasn't impressed at all.
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